From Plaster to Scaffold Tissue, a Medium to Heal Wound by UB Students

UB Students Invented Scaffold Tissue: Activator in Regeneration of Injured Skin

Plaster is the first thing to look for when a body part is scratched or similar. Basically the efficacy of plaster in helping wound healing because it is able to provide moist and sterile properties to the wound.

It can be interpreted here that the plaster has not specifically helped in terms of regeneration of the injured skin.

Four Chemical Engineering Students, Faculty of Mathematics and Natural Sciences Universitas Brawijaya (FMIPA UB) consisting of Nasirotul Wildah, Mahfita Ardyarum, Nabila Widadudari, and Ilhan Junio ​​Trizardi collaborated with students of the Faculty of Medicine (FK), Ulya Ahda Yustisia under the guidance of lecturer Supriyono, S.T., M.T innovated to create activators in the regeneration of injured skin.

The innovation is called as tissue scaffold, which will work by substituting the skin through the formation of temporary tissue during the wound.

“The effectiveness of this tissue scaffold is due to the use of hydroxyapatite (HA) material which is biocompatible so that it facilitates the distribution of cells in tissues that will grow without causing toxicity,” said Nasirotul as the team leader.

Synthetic hydroxyapatite material for scaffold tissue is in the form of nano-sized particles with a combination of silver chloride obtained through an electrochemical process. The low mechanical properties of hydroxyapatite are overcome by combining it with metals such as Ag contained in AgCl.

AgCl has antibacterial activity against gram negative and gram positive bacteria. AgCl can also easily enter the bacterial nucleus which can inhibit the growth mechanism.

“The Silver Chloride-Polyvinyl Alcohol (nHA/AgCl-PVA) Nano Hydroxyapatite Composite is made in the form of a membrane as a scaffold tissue preparation. The goal is that biomaterials can effectively stimulate the growth of injured skin tissue,” added Mahfita.

Through the scaffold tissue innovation, Nasirotul Wildah and the team hope that her team will have the opportunity to qualify for the 2022 National Student Scientific Week (PIMNAS). [Ulya/Irene/ Humas UB/ Trans. Iir]